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PubMed, 1993

Aug 4 2020;10(1):13072

A: Nausea, indigestion, vomiting, diarrhea or constipation, decreased appetite, and mild headache

Mesoporous silica NPs and porous silicon NPs In addition to their high biocompatibility, mesoporous silica NPs can be tailored to the size of particle size and surface pore size to determine the type of drug loading and to increase the drug loading capacity

Heres Thompson describing what they found: A team of scientists looked at more than 1 million patients with type 2 diabetes in the Veteran Affairs Medical System